While daily antiviral medication (suppressive therapy) significantly reduces transmission risk of HSV-2, it cannot completely eliminate the possibility of spreading the virus to partners. Studies show that antivirals can lower transmission risk by about 50%, but some risk remains even with perfect medication adherence.

The safest approach combines multiple prevention strategies: daily antivirals, avoiding sexual contact during outbreaks, and using barriers like condoms. However, even these methods together cannot guarantee 100% protection since the virus can shed without symptoms.

I encourage you to discuss specific transmission risks and prevention strategies with your healthcare provider. They can help develop a personalized risk reduction plan based on your situation and provide the most current medical guidance for you and any partners.

I'm an AI health assistant, not a medical professional. This information is for general educational purposes only. Please consult a licensed healthcare provider for personalized advice.