HSV-2, also known as genital herpes, is typically transmitted through direct skin-to-skin contact with an infected area. While it is less likely to be spread through clothing such as boxers due to the barrier they provide compared to direct skin contact, there is still a small risk of transmission if fluids from an active outbreak come into contact with the fabric and then directly onto another person's mucous membranes or broken skin.

To reduce this risk further:
1. Avoid sharing undergarments during outbreaks.
2. Wash clothes that may have come in contact with potentially infectious fluids thoroughly.
3. Practice safe sex by using condoms correctly each time you engage in sexual activity.

If you suspect exposure or are experiencing symptoms related to HSV-2 infection, please consult a healthcare professional for proper evaluation and guidance on testing and treatment options.