HSV-1 and HSV-2 are different strains of the herpes simplex virus that primarily affect specific areas.

HSV-1 usually causes oral herpes, commonly known as cold sores or fever blisters around the mouth and face.

On the other hand, HSV-2 typically leads to genital herpes with symptoms appearing in the genital area during sexual contact.

Both types can be transmitted through skin-to-skin contact but have distinct preferences for where they present their symptoms. It is important to get tested if you suspect you may have been exposed to either strain for appropriate management and treatment options from healthcare professionals.